Gene expression profiling in a mouse model of Dravet syndrome
نویسندگان
چکیده
منابع مشابه
Sudden unexpected death in a mouse model of Dravet syndrome.
Sudden unexpected death in epilepsy (SUDEP) is the most common cause of death in intractable epilepsies, but physiological mechanisms that lead to SUDEP are unknown. Dravet syndrome (DS) is an infantile-onset intractable epilepsy caused by heterozygous loss-of-function mutations in the SCN1A gene, which encodes brain type-I voltage-gated sodium channel NaV1.1. We studied the mechanism of premat...
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ژورنال
عنوان ژورنال: Experimental Neurology
سال: 2019
ISSN: 0014-4886
DOI: 10.1016/j.expneurol.2018.10.010